Showing posts with label image analysis. Show all posts
Showing posts with label image analysis. Show all posts

Bone Scans and DNA Testing by Major League Baseball

The New York Times published a very interesting piece a few days ago called Baseball's Use of DNA Raises Questions.

The impetus for these tests:
Dozens of Latin American prospects in recent years have been caught purporting to be younger than they actually were as a way to make themselves more enticing to major league teams.
Apparently, such players have been able to borrow the birth certificate of a younger child from some other family.

Can these tests actually reveal one's age? In the case of DNA, no. However, it can be used to check whether a given player is actually related to the parents listed on the birth certificate. According to the Times, this alone was enough to void the signing of a Yankee prospect last year from the Dominican Republic.

In the case of a bone "scan", I presume the Times actually means a bone age study, in which an X-ray of a subject's hand and wrist (and sometimes other body parts) is compared to a standardized atlas of age-matched X-rays for various ages. How reliable is a bone age study? Not very.

I interpret these occasionally in my practice. When I give my estimate of someone's skeletal age, it is accompanied with considerable variation -- usually one standard deviation equals about a year. In the specific case of a boy with a chronological age of exactly 16 years (192 months), the mean of the expected skeletal age is 195.3 months, where one standard deviation = 12.9 months. From these figures, we can calculate that 95 % of 16 year old boys should have a skeletal age varying between 169.2 and 220.8 months, i.e. 14.1 and 18.4 years old. This 95 % confidence interval of 4.3 years makes a bone age study pretty darned unreliable.

While bone age studies may be of dubious value, they don't lead to a lot of ethical dilemmas. DNA testing, on the other hand, does.

So far, MLB only seems to be using DNA testing to help verify a player's age. However, it's not hard to imagine how they might use other genetic information as well.
Mark Rothstein, a professor of bioethics at the University of Louisville School of Medicine, said: “The funny thing about this all is that the most famous baseball player with a genetic disorder was Lou Gehrig. Would they have signed him if they knew he was predisposed to A.L.S.?”

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